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(Injecting plain water in large volume would cause cells to swell and rupture due to osmotic imbalance, so sterile water is only given after adding an appropriate amount of solute to make it nearly isotonic

The route of administration, dosage, and injection technique all influence potential side effects

This combination of structural precision, reversibility-driven crystallinity, and tunable functionality makes COFs uniquely suited for rational design and targeted applications

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Experimental studies typically examine receptor-independent and receptor-associated signalling effects, transcriptional responses, and peptide stability under controlled conditions